Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Plaquenil et douleurs articulaires Hydroxychloroquine treats what conditions Medication for rheumatoid arthritis instead of plaquenil Chloroquine is a 9-aminoquinoline known since 1934. Apart from its well-known antimalarial effects, the drug has interesting biochemical properties that might be applied against some viral infections. Chloroquine exerts direct antiviral effects, inhibiting pH-dependent steps of the replication of several viruses including members of the flaviviruses, retroviruses, and coronaviruses. Its best. Chloroquine has not been formally assigned to a pregnancy category by the FDA. There are no controlled data in human pregnancies. Congenital anomalies were reported in the offspring of one woman being treated with chloroquine 250 to 500 mg daily during pregnancy for SLE; however, chloroquine has been used in the prophylaxis and treatment of malaria during pregnancy without evidence of fetal harm. Background/Purpose Chloroquine CQ and Hydroxychloroquine HCQ have been used for years during pregnancy for multiple indications malaria prevention, autoimmune disorders, etc. Recently, some countries face restrictions to prescribe these drugs during pregnancy, due to report of ocular toxicity in animal models and potential genotoxicity. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine and pregnancy Drug Safety in Pregnant & Nursing Women, Chloroquine Use During Pregnancy Malaria drug combined mice chloroquine 17Ophthalmologic complication of hydroxychloroquineChanges in taste and smell caused by hydroxychloroquine The CDC recommends continuing your other malaria treatment such as chloroquine throughout pregnancy until delivery to prevent harm to your unborn baby hemolytic anemia. After delivery, you may. Primaquine Oral Uses, Side Effects, Interactions, Pictures.. Safety of Chloroquine and Hydroxychloroquine During.. Dose Optimization of Chloroquine by Pharmacokinetic Modeling.. Anti-malarial drugs hydroxychloroquine, chloroquine are considered pregnancy category C drugs. While there is evidence of risk for damage to the eye and ear, if the benefits of these drugs in controlling RA symptoms are judged to outweigh the risks, they may continue to be used during pregnancy. 1,2. Tell your doctor if you have ever had vision changes while taking chloroquine phosphate, chloroquine hydrochloride Aralen HCl, or hydroxychloroquine Plaquenil. tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while using chloroquine phosphate, call your doctor. Hydroxychloroquine Pregnancy Warnings Animal studies have revealed evidence of fetal harm. Use of chloroquine and other 4-aminoquinolines in high doses and for prolonged durations has been associated with neurological disturbances and interference with hearing, balance, and vision in the fetus.