Although survival rates have improved, over one half of patients with systemic lupus erythematosus have permanent damage in one or more organ systems. Arthritis and cutaneous manifestations are most common, but renal, hematologic and neurologic manifestations contribute largely to morbidity and mortality. Can plaquenil cause bone loss Chloroquine pills given to troops in viet name Plaquenil increased appetite Chloroquine nivaquine is an antimalarial drug used in the treatment and prophylaxis of uncomplicated malaria, extraintestinal amebiasis and discoid lupus. Hydroxychloroquine and chloroquine phosphate have shown beneficial effects in treating discoid lupus erythematosus DLE. Additionally, The antimalarial drugs may prevent the development of systemic lupus erythematosus SLE in patients with DLE, and they might decrease the risk of cardiovascular disease. Alternative therapies, anecdotal reports, and small, open-label trials as reported by. Use For lupus erythematosus chronic discoid and systemic in patients who have not responded satisfactorily to drugs with less potential for serious side effects. Usual Adult Dose for Rheumatoid Arthritis-Initial dose 400 to 600 mg 310 to 465 mg base orally once a day to optimum response usually 4 to 12 weeks Systemic lupus erythematosus has fascinated physicians for almost a century and remains the prototypic autoimmune disease. Treatment approaches emphasize using a combination of drugs to minimize chronic exposure to corticosteroids. Chloroquine for discoid lupus Aralen chloroquine Malaria Drug Side Effects & Dosage, Discoid Lupus Erythematosus Medication Antimalarial. Chloroquine dna supercoilingPlaquenil and essential oilsPlaquenil and citalopram qt prolongationWhy chloroquine has high volume of distribution Cutaneous lupus erythematosus CLE is an autoimmune, inflammatory skin disease seen in patients with or without systemic lupus erythematosus SLE. The management of CLE includes treatment and prevention of lesions, as well as routine assessment for systemic disease. Treatment options include both topical and systemic therapies. Treatment of Cutaneous Lupus. Hydroxychloroquine Dosage Guide with Precautions -. Treatment of Cutaneous Lupus Erythematosus. Chloroquine is a synthetic antimalarial medication that was first developed in 1934. In addition to its antimalarial effects, chloroquine has been used extensively in rheumatology and dermatology since the 1950s. Discoid lupus erythematosus. Reticular erythematous mucinosis. Original Article from The New England Journal of Medicine — Chronic Discoid Lupus Erythematosus — Treatment with Daraprim and Chloroquine Diphosphate Aralen Chloroquine phosphate is used occasionally to decrease the symptoms of rheumatoid arthritis and to treat systemic and discoid lupus erythematosus, scleroderma, pemphigus, lichen planus, polymyositis, sarcoidosis, and porphyria cutanea tarda. Talk to your doctor about the possible risks of using this drug for your condition.