The reaction can be phototoxic and/or photoallergic. Phototoxic reactions result from direct damage to tissue caused by light activation of the photosensitising agent, whilst photoallergic reactions are a cell-mediated immune response in which the is the light-activated photosensitising agent. Plaquenil and elavil Plaquenil pain medication Plaquenil ilm degeneration Hydroxychloroquine class action lawsuit Dec 12, 2019 In a double-blinded study, this drug was found to be more phototoxic than minocycline and demeclocycline. Paresthesias of the body areas exposed to sunlight may be early signs of sunburn reactions. A case report of a possible photoallergic reaction described scaly erythema and vesicles on the face and neck associated with administration of this drug. This reaction is called phytophotodermatitis. All phototoxic reactions appear only on areas of skin that have been exposed to the sun. They usually develop within hours after sun exposure. In photoallergy, an allergic reaction causes redness, scaling, itching, and sometimes blisters and spots that resemble hives. The reaction can be phototoxic and/or photoallergic. Phototoxic reactions result from direct damage to tissue caused by light activation of the photosensitising agent, whilst photoallergic reactions are a cell-mediated immune response in which the antigen is the light-activated photosensitising agent. Although some oral photosensitising medications can cause photoallergic reactions, most cause phototoxic reactions. Photoallergic reactions occur less commonly than phototoxic reactions and are mostly caused by photosensitising topical agents. Phototoxic reaction to plaquenil Migraine Medications and the Risk of Sun Sensitivity A List, Photosensitivity Reactions - Skin Disorders - Merck Manuals. Who should not take plaquenil Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Drug-induced photosensitivity DermNet NZ. Drug-induced photosensitivity Photoallergic and phototoxic.. The clinical features of photocontact dermatitis vary according to the photosensitising agent involved and the type of reaction it causes in the skin. A phototoxic reaction generally appears similar to a bad sunburn. A photoallergic reaction generally presents as eczema also called dermatitis confined to the areas in contact with the. A doctor suspects a photosensitivity reaction when a rash appears only in areas exposed to sunlight. A close review of the person's medical history, skin symptoms, any diseases, drugs taken by mouth, or substances applied to the skin such as drugs or cosmetics may help a doctor pinpoint the cause of the photosensitivity reaction. Feb 19, 2020 PLAQUENIL should be administered with caution in patients having glucose-6-phosphate dehydrogenase G-6-PD deficiency. Dermatologic Effects. Dermatologic reactions to PLAQUENIL may occur and, therefore, proper care should be exercised when it is administered to any patient receiving a drug with a significant tendency to produce dermatitis.