It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Effects of plaquenil on teeth Plaquenil renal dosing The purpose of this study is to compare the incidence of congenital defects, spontaneous abortions, number of live births, fetal death and pre-maturity in women with autoimmune diseases taking HCQ during pregnancy. The authors searched MEDLINE, Cochrane data base, Ovid-Currents Clinical Medicine, Ovid-EmbaseDrugs and Pharmacology, EBSCO, Web of Science, and SCOPUS using the search terms HCQ. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine Pregnancy Warnings Animal studies have revealed evidence of fetal harm. Use of chloroquine and other 4-aminoquinolines in high doses and for prolonged durations has been associated with neurological disturbances and interference with hearing, balance, and vision in the fetus. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Pregnancy category hydroxychloroquine AB0372 Safety of hydroxychloroquine in pregnant women with., Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Can i take tamiflu with hydroxychloroquineCan you take tylenol while taking plaquenilHydroxychloroquine and skin hardeningChloroquine dna supercoiling PLAQUENIL® HYDROXYCHLOROQUINE SULFATE, USP WARNING PHYSICIANS SHOULD COMPLETELY FAMILIARIZE THEMSELVES WITH THE COMPLETE CONTENTS OF THIS LEAFLET BEFORE PRESCRIBING HYDROXYCHLOROQUINE. DESCRIPTION Hydroxychloroquine sulfate is a colorless crystalline solid, soluble in water to at least 20 PLAQUENIL® - Food and Drug Administration. Hydroxychloroquine Use During Pregnancy. Hydroxychloroquine Uses, Dosage & Side Effects -. OBJECTIVE The use of hydroxychloroquine HCQ in pregnancy remains controversial. The recent demonstration that HCQ passes across the placenta, with cord blood concentrations nearly identical to those found in maternal blood, emphasizes the need for careful evaluation of pregnancies in women receiving HCQ. Anti-malarial drugs hydroxychloroquine, chloroquine are considered pregnancy category C drugs. While there is evidence of risk for damage to the eye and ear, if the benefits of these drugs in controlling RA symptoms are judged to outweigh the risks, they may continue to be used during pregnancy. 1,2 Abstract. OBJECTIVE To study maternal and fetal outcome of pregnancy in patients with lupus who were exposed to hydroxychloroquine HCQ. METHODS The case records of women n = 33 exposed to HCQ during their pregnancies n = 36 and of 53 control patients from a single lupus pregnancy centre were reviewed to determine lupus activity, obstetric experience, and infant outcome.