Additionally, another exception occurred while executing the custom error page for the first exception. This is not a list of all drugs or health problems that interact with Plaquenil (hydroxychloroquine). Hydroxychloroquine chemotherapy Reactions to plaquenil Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells. Rare but potentially serious eye toxicity can occur. This toxicity affects a part of the eye called the retina and can lead to color blindness and even loss of vision. An. This means many people taking Plaquenil for RA are taking a dose of 400mg a day or higher. Pigment deposits in the retina can cause vision changes, according to Steven Ofner, M. D. of Eugene Oregon Eye Care. Signs of retinal damage include blurry or distorted vision, flashes of light or floaters, or loss of night vision. Find information about common, infrequent and rare side effects of Plaquenil Oral. You must check to make sure that it is safe for you to take Plaquenil (hydroxychloroquine) with all of your drugs and health problems. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Does plaquenil cause eye problems Protecting your eyesight when taking Plaquenil Lupus., Long-Term Side Effects of Plaquenil for Rheumatoid. Will plaquenil help anemia Please note the rare side effects listed below, specifically retinopathy, which causes damage to the eyes. Side effects associated with Plaquenil are placed in three categories common, less common, and rare. If you have any of the following effects and they persist or worsen, notify your doctor or pharmacist promptly. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Common and Rare Side Effects for Plaquenil Oral. Will you have Vision problems with Plaquenil - eHealthMe. Plaquenil can cause serious vision problems that aren't always reversible. Tell your doctor immediately if you notice any changes in vision or if you've ever had vision changes while taking. Its most frequent use now is for Rheumatoid Arthritis RA and Lupus and is often very effective in mitigating the joint and arthritic symptoms these diseases can cause. One of the most significant side effects of the drug is its possibility of causing eye problems resulting in blurred or decreased vision. The most common issue is damage to the. Plaquenil eye problems. Posted by Wesbig @wesbig, Jul 25, 2016. I was wondering if anyone experienced blurry vision on Plaquenil. I have been on Plaquenil for about a month. Every now and then I notice some of the words on the television are blurry, then there are other times my eyes are fine. Should this be a big concern?