Plaquenil was the only drug for me which gave me instantaneous better saliva flow improved my depression within a week. The downside: I got a severe allergic reaction, eye trouble, enormous chills, constipation, weight gain and anorgasmia... Plaquenile alcohol Plaquenil pulmonary Cutting back on plaquenil Chloroquine for lupus treatment Plaquenil Hydroxychloroquine is used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus & others. The alternative to Plaquenil is a slightly different anti malarial called Quinacrine. Plaquenil replaced Quinacrine formerly called Atabrine for anti malarial prophylaxis so now the Quinacrine has to be made up into pills or gel capsules by a compounding pharmacy. If you google you will find details of compounding pharmacies. Hydroxychloroquine generally does not have significant interactions with other medications, but care should be taken if combined with medication altering liver function as well as aurothioglucose Solganal, cimetidine Tagamet or digoxin Lanoxin. Pilocarpine, thyroid meds, 25mg quetiapine, 1% testosterone. DES-daughter ('67), Lyme's ('98), GAD ('98), Sjogren's ('02), hypothyroid ('04), endometriosis ('14), osteoarthritis ('16), blepharitis ('18), frozen shoulder ('19). So please anyone, is there something else which can 'kill the bugs' inside me? DES-daughter ('67), Lyme's ('98), GAD ('98), Sjogren's ('02), hypothyroid ('04), endometriosis ('14), osteoarthritis ('16), blepharitis ('18), frozen shoulder ('19). Hydroxychloroquine alternative Compare Plaquenil vs Chloroquine -, Discontinued Plaquenil.other options? Is plaquenil free at publixPlaquenil side effects mood changes Here are the three most common antimalarial drugs prescribed for lupus Hydroxychloroquine Plaquenil This is the most commonly prescribed antimalarial. Chloroquine Aralen This drug has been known to have more serious side effects. Quinacrine Atabrine Quinacrine is another. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Hydroxychloroquine - Wikipedia. Plaquenil Shortage Leaves RA, Lupus Patients in Pain and.. Apr 02, 2010 there are several drugs now that you can take instead of the plaquenil. these type of drugs they have now work in a different way then the methotrexate and plaquenil. most of these drugs you will still take the methotrexate. i researched these drugs before i made my decision and so for myself i started on the enbril and boy what a difference. I have taken Plaquinel/hydroxychloroquine at a low dose as maintenance for my SLE for over 20 years. No side effects. No problems. Until I went on Medicare and they don't want to pay for it. They want me to try cheaper alternatives before they will pay for hydroxychloroquine. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus.