The patient had been treated with hydroxychloroquine for two years prior to presentation. After thorough workup for secondary causes of QT interval prolongation hydroxychloroquine was discontinued and the patient’s QT interval shortened. Plaquenil and voice issues Does plaquenil increase the likelihood of getting a cold Map of chloroquine resistant malaria Feb 19, 2020 As PLAQUENIL may enhance the effects of a hypoglycemic treatment, a decrease in doses of insulin or antidiabetic drugs may be required. Drugs That Prolong QT Interval And Other Arrhythmogenic Drugs. PLAQUENIL prolongs the QT interval and should not be administered with other drugs that have the potential to induce cardiac arrhythmias. Long-term therapy in children • children under 6 years of age. 4.4 SPECIAL WARNINGS AND PRECAUTIONS FOR USE Plaquenil is not effective against chloroquine-resistant strains of P.falciparum. Patients should be warned to keep Plaquenil out of the reach of children, as small children are particularly sensitive to the 4-aminoquinolines. Feb 19, 2020 SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. The patient was noted to have mild prolongation of the QT interval on electrocardiogram prior to initiation of hydroxychloroquine therapy which was exacerbated by its use and may have been caused due to toxicity from underlying renal failure. The patient was treated with mexiletine to prevent sudden ventricular arrhythmias, which was unique compared to other documented cases in which lidocaine was used. Plaquenil and log qt Drugs to be avoided in patients with long QT syndrome Focus., DATA SHEET 1 PRODUCT NAME 2 QUALITATIVE AND QUANTITATIVE. Effect of plaquenil on free light chainsChloroquine against malariaAralen side effects and instructionsHydroxychloroquine discoid lupusHydroxychloroquine retinal COMBINED LIST OF DRUGS THAT PROLONG QT AND/OR CAUSE TORSADES DE POINTES TDP CredibleMeds® has reviewed available evidence for the drugs on the following list and place them in one of three designated categories Known Risk of TdP KR, Possible Risk of TdP PR or have a Conditional Risk of TdP CR. The full description of these CredibleMeds® has reviewed available evidence for the drugs.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Long QT and Hydroxychloroquine; A Poorly Recognised.. Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. However, following an identical dose of. Page 4 of 26 PLAQUENIL is not recommended for use in patients with baseline QTc prolongation e.g. congenital or acquired Long QT Syndrome, second-or third-degree atrioventricular block. Long qt syndrome is found among people who take Plaquenil, especially for people who are female, 60+ old also take medication Quinine, and have Muscle spasms. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly.