See below for a comprehensive list of adverse effects. Applies to methotrexate: oral solution, oral tablet Other dosage forms: Oral route (Solution) Severe Toxic Reactions, Including Embryo-Fetal Toxicity Methotrexate can cause severe or fatal toxicities. Malaria medicine hydroxychloroquine Plaquenil during pregnancy The effects of methotrexate and hydroxychloroquine combination therapy vs methotrexate monotherapy in early rheumatoid arthritis patients. Folic acid 10 mg/week is standard-prescribed to minimize MTX side effects. At start of treatment, patients are offered corticosteroid treatment, either intramuscular methylprednisolone injection 120 mg. Too many side effects of both methotrexate and Hydrochloroquine prompted my beautiful daughter to encourage me to go on a strict diet with no meds. I did check with my gp and rheumy re this. I am now thank God in remission 🌸 Methotrexate does suppress the immune system, but serious infections with methotrexate are not common. Your rheumatologist will monitor you closely for any side effects associated with methotrexate such as liver test abnormalities, pneumonitis, or infections. Methotrexate can cause embryo-fetal toxicity and fetal death. Monitor closely and modify dose or discontinue for the following toxicities: bone marrow suppression, infection, renal, gastrointestinal, hepatic, pulmonary, hypersensitivity and dermatologic. Methotrexate vs plaquenil side effects long term Major side effects of low-dose methotrexate - UpToDate, Does anyone take methotrexate and hydroxychloroquine. - NRAS Biaxin and plaquenil lyme diseasePlaquenil lip swellingBiaxin plaquenil lymeWithdrawal effects of plaquenilMycophenolate and plaquenil SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Methotrexate side effects - Arthritis Information. Methotrexate vs plaquenil side effects long term and short term. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. I saw him three weeks ago, and he encouraged me to try to taper down now that the plaquenil is helping so much. According to him, only doses lower than 3 mg per day can be considered to have zero long-term side effects, so he either wants me off the steroids completely, or to get at or below 3 mg. Find information about common, infrequent and rare side effects of Methotrexate Anti-Rheumatic Oral.