In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Statistics plaquenil maculopathy Hydroxychloroquine and doxycycline Hydroxychloroquine lichen planopilaris Does Plaquenil cause Hyperpigmentation? Last Update September 23, 2018. Treato found 37 posts discussing Plaquenil and Hyperpigmentation. Sjogren's Syndrome and Joint Pain and is mostly mentioned together with these indications. Read More. See more about. Plaquenil Hyperpigmentation All side effects & concerns. Conquering Sjogren’s Follow us on our journey to change the face of Sjogren’s. The Risk of Retinal Toxicity with Plaquenil. Posted on Fri, Aug 29, 2014 Tweet; Plaquenil, hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, systemic lupus. Hydroxychloroquine is an antimalarial medication that can cause hyperpigmentation of nails, mucosa, and skin 1–5. Retrospective studies cite the incidence of drug-related hyperpigmentation from hydroxychloroquine to be as high as 33% of individuals. Elder abuse is a cause of significant morbidity and mortality in older individuals 7–9. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Plaquenil and hyperpigmentation sjogren's Hydroxychloroquine An old drug with new relevance Cleveland Clinic., The Risk of Retinal Toxicity with Plaquenil - Sjogren's Differential diagnosis for plaquenil retinopathy Today, Plaquenil and other antimalarials are also used to treat and help prevent symptoms caused by certain autoimmune diseases such as rheumatoid arthritis RA, systemic lupus erythematosus, and discoid lupus, even though these diseases are not caused by malaria parasites. Plaquenil belongs in a class of medications known as disease-modifying. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Hydroxychloroquine-Associated Hyperpigmentation Mimicking.. Skin Pigmentation with Hydroxychloroquine Plaquenil.. In a variety of Connective Tissue Diseases a broad group of autoimmune disease I thought these photos were worth posting. The patient has rheumatoid arthritis and is actually on Hydroxychloroquine as monotherapy due to a number of other diseases restricting our use of other disease-modifying agents. Study Raises Questions about Sjogren's and Plaquenil Image Source For many patients with Sjogren's, Plaquenil hydroxychloroquine has long been the go to drug that their doctors prescribe. It is often the first line of attack before other more aggressive therapies are added such as methotrexate or rituximab that have bigger impacts on the. I've been on Plaquenil about 2 months, and it has helped my knee/back pain, which is wonderful. I get the hyperpigmentation, too, but it is mostly on just my arms. Instead of brown spots, I get solid dark brown arms, but I have little spots on my arms with NO pigment, so there are white polka dots. Plaquenil and skin discoloration. SMF.