Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Can hydrocodone and hydroxychloroquine be taken together Hydroxychloroquine sudden neck stiff neck pain Plaquenil or hydroxychloroquine HCQ is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid The Risk of Retinal Toxicity with Plaquenil YOUR CREDIBLE SJÖGREN'S RESOURCE Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Visual defects hydroxychloroquine Retinal Physician - Hydroxychloroquine Maculopathy An Update., Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Ra medicine hydroxychloroquine Sep 13, 2019 Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Hydroxychloroquine Side Effects Common, Severe, Long Term.. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. HYDROXYCHLOROQUINE - Hydroxychloroquine sulfate. Conclusions The current study used a protocol of visual acuity and color vision assessment, funduscopy, and Humphrey 10-2 visual field testing and shows that visual field defects appeared before any corresponding changes in any other tested clinical parameters; the defects were reproducible and the test parameters were reliable. Patients taking hydroxychloroquine can demonstrate a toxic reaction in the retina despite the absence of known risk factors. This is ordered for the 10% of glaucoma patients who are so advanced that the HVF 24-2 is mostly black, with only a central island of remaining vision. Macular diseases including plaquenil toxicity exams also need 10-2. HVF 30-2. Generally, we order this for neuro patients. It has a wider angle and can capture peripheral field defects. Sep 13, 2019 Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.