There are hundreds of drugs with potential retinal toxicity—so many that the National Registry of Drug-Induced Ocular Side Effects doesn’t stratify them by incidence or effect, said Frederick W. “Rick” Fraunfelder, MD, director of the Registry and associate professor of ophthalmology at Oregon Health & Science University in Portland. Chloroquine retinal cell Long term chloroquine effects Hydroxychloroquine and myasthenia gravis Does hydroxychloroquine tabs disrupt immune system Ocular side effects associated with chloroquine can be primarily divided into keratopathy, ciliary body changes, and retinopathy. Bull's eye maculopathy, a type of retinopathy, is associated with the use of antimalarial agents and is relatively rare. Like all medicines, it can cause side effects. Hydroxychloroquine retinopathy It is known that some people who take hydroxychloroquine for more than five years and/or in high doses are at increased risk of damage to their retina, the light sensitive layer of cells at the back of the eye. This is known as retinal toxicity or retinopathy. Download PDF. Drug-induced ocular side effects are back in the spotlight, thanks to the Academy’s revision of its recommendations on screening for retinal toxicity from chloroquine and its analogue hydroxychloroquine Plaquenil. 1 There are hundreds of drugs with potential retinal toxicity—so many that the National Registry of Drug-Induced Ocular Side Effects doesn’t stratify them by. “It’s a pretty rare thing.” Nevertheless, he urged doctors to master the Academy’s new guidelines, because the effects from chloroquine and hydroxychloroquine, when they do occur, are severe and often irreversible. “Plaquenil toxicity isn’t even in the top 10, or the top 100” if you’re looking at incidence, he said. Pics of ocular side effects chloroquine corneal damage Chloroquine Oral Uses, Side Effects, Interactions., Eye screening for patients taking hydroxychloroquine Plaquenil Generic vs brand name plaquenil Nov 15, 2017 Glaucoma Therapy Don’t Forget the Ocular Surface Following the mantra “do no harm” can be a challenge when prescribing topical glaucoma medications. These tips can help minimize damage. By Leslie O’Dell, OD, and Ben Gaddie, OD Glaucoma Therapy Don’t Forget the Ocular Surface. Rx Side Effects New Plaquenil Guidelines and More.. Plaquenil Side Effects on Your Eyes and Vision. Chloroquine Aralen is used for preventing and treating malaria and amebiasis, an infection of the intestines caused by a parasite. Chloroquine Aralen - Side Effects, Dosage, Interactions. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Subscribe. Eye damage risk. The Ocular Surface Drug toxicity to the ocular surface can manifest as epithelial keratopathy, corneal edema and altered tear film quantity and quality. 5 Timely and appropriate management of these complications can prevent permanent ocular surface damage and impaired vision. Early recognition can ensure the patient is able to continue the appropriate treatment for their underlying disorder.