Typically, it results from improper absorption of fats in your lower intestines. When the poorly digested fats get into the small intestines, they are passed out of the digestive system in form of lose yellow fecal matter. Restarting plaquenil Hydroxychloroquine 200 mg for rheumatoid arthritis dose Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Find information about common, infrequent and rare side effects of Plaquenil Oral. Apr 21, 2017 I had severe nausea and diarrhea when started on Plaquenil 2 X 200mg tabs once daily almost 3yrs ago. As I also have Crohn's Disease and an Ileostomy this was putting me at serious risk. I was told to stop the Plaquenil until my GI symptoms disappeared. The causes of yellow diarrhea include: Normal poop is brown in color because it contains bile salts or bile pigments. In some cases, the yellow stool may be accompanied with fat droplets. Plaquenil and yellow diarrhea Hydroxychloroquine Oral Route Side Effects - Mayo Clinic, Common and Rare Side Effects for Plaquenil Oral Chloroquine side effects in children Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Plaquenil aka HCQS – Anyone on this getting severe diarrhea.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Quinacrine Atabrine Quinacrine is another alternative, but it is prescribed less often because it can sometimes cause a yellow discoloration of the skin. It is sometimes given in addition to hydroxychloroquine if the Plaquenil on its own is not adequately managing symptoms. Ginny, I had some very minor diarrhea, nausea, cramping for about a week when I started Plaquenil. Everyone is different, but for me, taking the med about 15 min. after eating, rather than before or with a meal, makes things much easier on my stomach, even for just Advil. Nov 09, 2018 Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria.