I started on it just less than 2 weeks ago, and I'm surrounded by ill people at work and already have a bit of a cold (nothing severe). it is "milder" than a lot of the other dmards in terms of side effects and activity x It is listed as having a mild immunosuppressant effect in my book on RA, but one of the reasons for the blood tests is to check that your immune system is not being suppressed too much (eg checking your white blood cell levels), so you shouldn't be completely vulnerable. Even after several years of taking lots of drugs I've not found any difference in the number of colds etc I get, and loads of people on here are teachers etc who get a lot of exposure to colds and coughs without too much problem. Diluting chloroquine for in vivo treatments Nabumetone lupus hydroxychloroquine Long term effects of plaquenil Side effects of malaria pills chloroquine I'm not a healthcare provider, but I do take Plaquenil and just found out from another user of it that it does suppress the immune system. I didn't know that when I started taking it for Sjogren's in November 2011. It is listed as having a mild immunosuppressant effect in my book on RA, but one of the reasons for the blood tests is to check that your immune system is not being suppressed too much eg checking your white blood cell levels, so you shouldn't be completely vulnerable. Dear Dr. Aviva, Given I am 56 and have Hashimoto's - an autoimmune condition - am I at higher risk - for getting COVID-19? Should those of us with autoimmune conditions consider that to be an “underlying condition” that puts one at higher risk of having a more severe reaction if infected with the coronavirus. Thank you so much for Polly Thank you both, I thought it shouldn't be too bad and that it's pretty mild in comparison to other drugs. Always better to be well informed and I remember the consultant saying its bit a bad time of year to start on it as I've missed all the bugs round Christmas time so thought there may be a slim chance of it being suppressed. But do look after yourself, and make sure you eat well and don't get too tired as if you have a cold already you need to pamper yourself a bit more than you would have before RA. Does plaquenil suppress your immune system Methotrexate Does it weaken my immune system?, Hydroxychloroquine and the immune system Hi everyone. Would chloroquine in a sickle cell patient beh harfmulPlaquenil for infertility Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. A rare side effect of Plaquenil involves visual changes or possible loss of vision —the side effect that is most worrisome for patients. Taking Plaquenil for Rheumatoid Arthritis. COVID-19 and Autoimmune Disease Risk It Depends on the.. Antimalarial Medications RDS. Plaquenil works by suppressing the immune system. Unfortunately you can't tell it to attack just the germs so you suppress all of its function to spare your healthy tissue- in your husband's case, his eyes, mouth, throat. NOTE Plaquinil and hydroxychloroquine are essentially the same drug. The same effects should be expected from both drugs. 2. No, his immune system should not be forever compromised. Overall, most serious fungal infections are rare, but they do happen. They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at risk for fungal infections. My gyn oncologist was concerned that the Plaquenil may affect my immune system to ward of the hpv since we all know a good immune system is needed to fight the virus --- He understands the RA pain conundrum I have.