Iupac name of chloroquine

Discussion in 'Canadian Pharmacy Drugs Online' started by ashurge, 05-Mar-2020.

  1. YIO Well-Known Member

    Iupac name of chloroquine


    It is bioactivated hepatically to its primary metabolite, N-desethylamodiaquine, by the cytochrome p450 enzyme CYP2C8. Among amodiaquine users, several rare but serious side effects have been reported and linked to variants in the CYP2C8 alleles.

    Hydroxychloroquine ibuprofen interaction Plaquenil tablets covis Is hydroxychloroquine a hydrocodone

    The PDB entry listed in the links table is for R-chloroquine. Marketed formulations may contain chloroquine phosphate PubChem CID 64927. The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY. Structure, properties, spectra, suppliers and links for Chloroquine diphosphate, 50-63-5, Chloroquine Phosphate. Chloroquine is a 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite.

    People who are poor metabolizers of amodiaquine display lower treatment efficacy against malaria, as well as increased toxicity. CYP2C8*1 is characterized as the wild-type allele, which shows an acceptable safety profile, while CYP2C8*2, *3 and *4 all show a range of "poor metabolizer" phenotypes.

    Iupac name of chloroquine

    Chloroquine - wikidoc, Chloroquine diphosphate C18H32ClN3O8P2 ChemSpider

  2. Treatment of uncomplicated malaria chloroquine
  3. Name; Formula; IUPAC identifier; CAS number; More options; NIST Data. IUPAC Standard InChIKey WHTVZRBIWZFKQO-UHFFFAOYSA-N; CAS Registry Number 54-05-7; Chemical structure This structure is also available as a 2d Mol file;. Capquin; Cloroquine; Ronaquine; +/--Chloroquine.

    • Chloroquine - NIST.
    • Chloroquine C18H26ClN3 - PubChem.
    • Chloroquine sulfate C18H28ClN3O4S - PubChem.

    Name Chloroquine phosphate Drug Entry Chloroquine. Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. 4 It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. 17 Chloroquine was granted FDA Approval on 31 October 1949. 19 The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses. Name Chloroquine sulfate Drug Entry Chloroquine. Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. 4 It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. 17 Chloroquine was granted FDA Approval on 31 October 1949. 19

     
  4. bas82 New Member

    Background: The American Academy of Ophthalmology recommendations on screening for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. PATIENT FACT SHEET Hydroxychloroquine Plaquenil Shared Care Guideline - mm.uk HYDROXYCHLOROQUINE Shared Care Guideline V1
     
  5. .Edâ„¢ Guest

    Hydroxychloroquine - Side Effects, Dosage, Interactions. Nov 09, 2018 Hydroxychloroquine can cause serious liver or heart problems, especially if you use certain medicines at the same time, including other medicines to treat malaria; an antibiotic or antifungal.

    Hydroxychloroquine Oral Route Description and Brand Names.
     
  6. Krieg Well-Known Member

    Hydroxychloroquine - Wikipedia Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth.

    Chloroquine - Wikipedia