She had been taking hydroxychloroquine as a disease-modifying agent for about 15 years. A transthoracic echocardiogram showed reduced left ventricular function with an ejection fraction of 35% (A, Online Video 1). Hydroxychloroquine blood monitoring What does plaquenil look like Plaquenil tamoxifen symptoms reticulocytosis Hydroxychloroquine effect on platelets Hydroxychloroquine induced myopathy is rare adverse reaction but symptoms are usually recover after discontinuation of the drug. Here we report a case of woman with systemic lupus erythematosus who presented with myopathy after eight months treatment with hydroxychloroquine. In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Introduction. Hydroxychloroquine HCQ is one of the antimalarial drugs that have been used for decades to treat rheumatic diseases. Retinal toxicity, neuromyopathy, and cardiac toxicity are recognized toxicities following prolonged use. HCQ-induced cardiomyopathy is one of the rare but severe complications which could be reversible with early withdrawal of the drug. Periodic-acid Schiff staining showed glycogen deposition in myocyte cytoplasm. Subsequent coronary angiography revealed normal coronary arteries. Hematoxylin and eosin staining revealed myocyte vacuolization (B). Plaquenil induced cardiomyopathy Chloroquine‐induced cardiomyopathy a reversible cause of heart failure., Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs Plaquenil e alopeciaDoes plaquenil thin the blood New clinical and ultrastructural findings in hydroxychloroquine-induced cardiomyopathy a report of 2 cases. Hum Pathol. 2007; 58–1863. Hydroxychloroquine-Induced Cardiomyopathy Circulation Heart Failure. Hydroxychloroquine-induced cardiomyopathy and heart.. PDF Hydroxychloroquine-Induced Cardiomyopathy A Case Report. Soong TR, Barouch LA, Champion HC et al 2007 New clinical and ultrastructural findings in hydroxychloroquine-induced cardiomyopathy—a report of 2 cases. INTRODUCTION. Although the precise incidence is unknown, drug-induced myopathy is among the most common causes of muscle disease. Drug-induced myopathy ranges from mild myalgias with or without mild weakness to chronic myopathy with severe weakness and to massive rhabdomyolysis with acute renal failure 150 agents have been associated with rhabdomyolysis. On the basis of these classic findings, a diagnosis of hydroxychloroquine cardiomyopathy was made, and the drug was discontinued. Three months later her symptoms had completely resolved. Repeat imaging using cardiac magnetic resonance demonstrated an ejection fraction of 65% D, Online Video 2.