I'm not completely pain free, but it's a lot better than it was. I've been on plaquenil since mid June I have had a lot of stress in my life so I can't determine what is causing what. Not seeing any improvements with pain but I just went to 0 prednisone 3 weeks ago. said give it a few months and if I don't see any improvement I might as well go off of it. Wanted to let you know that I was on plaquenil for about three years and I told my RA doctor that my fatigue was worse. It just seems like the fatigue is worse than it has ever been, and it doesn't seem to matter if I go to bed early or take a nap during the day. Woke up and cleaned the kitchen an hour later(my kitchen is a galley kitchen 8 ft maybe.no time) Took a nap. Early on I did get those stomach cramps and diarrhea. All my pain is tolerable and he sees no deformities so he says he doesn't see RA activity. Just because the pain is tolerable doesn't make me like it any better. He did a plaquenil test and sure enough it was low. Plaquenil and antidepressants Plaquenil treat lupus Plaquenil and Drowsiness - from FDA reports Summary Drowsiness is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 1 month, also take medication Enbrel, and have Pain. The effects of overdosage with hydroxychloroquine include headache, drowsiness, visual disturbances, convulsions, cardiovascular collapse, and respiratory arrest. Toxic retinopathy has also been associated with higher doses and longer duration of use. Hydroxychloroquine oral tablet doesn’t cause drowsiness, but it can cause other side effects. More common side effects. The more common side effects that can occur with hydroxychloroquine include I wake up tired in the morning, get my kids fed and off to the schoolbus, and some days that's all I can do until it's time to go pick them up and make dinner, then I collapse after the kids are put to bed. I don't know if this is just the way RA is, or if it is a side effect of the medicine. Wasn't going to eat luch because I would have to move to do it.husband bought out. Kids came home, helped with homewrok, made dinner..picked up couch(because my blanket and pillow were there) Went to bed at 9. Drowsiness hydroxychloroquine HYDROXYCHLOROQUINE - ORAL Plaquenil side effects, medical., HCQ - Clinical Hydroxychloroquine, Serum Bull's eye maculopathy plaquenilChloroquine autophagy protocolAmerican academy of ophthalmology plaquenil guidelinesAao 2016 plaquenil A 16-year-old girl presented to the emergency department ED with a blood pressure of 63 mm Hg by palpation, pulse of 110 beats/min, slurred speech, and drowsiness. History revealed she had taken a handful of her hydroxychloroquine 200 mg, levothyroxine, aspirin, and ibuprofen, 30 minutes before presentation. Treatment of hydroxychloroquine overdose - ScienceDirect. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxychloroquine - Side Effects, Dosage, Interactions.. HYDROXYCHLOROQUINE is used to treat rheumatoid arthritis and systemic lupus is also used to treat malaria. The lowest GoodRx price for the most common version of hydroxychloroquine is around $20.41, 88% off the average retail price of $177.73. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. An overdose of hydroxychloroquine can be fatal, especially in children. Hydroxychloroquine overdose must be treated quickly. You may be told to induce vomiting right away at home, before transport to an emergency room. Ask the poison control center how to induce vomiting in the case of an overdose.