She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation. Can i take zyrtec with plaquenil Plaquenil cream Effects of plaquenil Stopped prior to retinal pigment epithelial damage or bull’s eye maculopathy, retinal findings may remain stable without progression5. In addition, most patients with retinal toxicity have no visual symptoms until severe damage is done. Therefore early screening is essential. New objective screening modalities including spectral domain optical While Plaquenil can cause a variety of symptoms, most of them are minor and temporary. The most serious symptom, however, is neither minor nor temporary. Permanent, vision-altering retinal damage has been documented in some long-time users of Plaquenil, but it has been regarded as rare, as long as patients use doses appropriate to their mass. Plaquenil is the devil! Worked well 1st 2 mts. After that I had issues with my vision, felt waves of nervousness, and extreme anxiety where I started to question my sanity. Hallucinated, broke out in rashes and crying spells. Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use. Symptoms of retinal damage from plaquenil Does Patient with Lupus Have Plaquenil Retinopathy?, Plaquenil toxicity and lowering dosage What You Sjo Fundus autofluorescence plaquenil Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil Oral Uses, Side Effects, Interactions, Pictures, Warnings.. Plaquenil oral Reviews and User Ratings Effectiveness, Ease of Use.. Plaquenil Uses, Dosage & Side Effects -. Aug 29, 2014 This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The side effect that is of greatest concern is retinal toxicity. Retinal detachment is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years, also take medication Concerta, and have Joint deposit Hydroxychloroquine is an effective and relatively safe drug that can cause retinal toxicity in a minority of patients. Early diagnosis is important to stop treatment and prevent possible further damage.