Plaquenil ophthalmology

Discussion in 'Chloroquin' started by senche, 10-Mar-2020.

  1. zombi User

    Plaquenil ophthalmology


    Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight.

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    Jan 05, 2020 Hydroxychloroquine is a well-tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity1. Within the eye, hydroxychloroquine can adversely impact the cornea, ciliary body, and retina1 Plaquenil Hydroxychloroquine is used to dampen inflammation in some forms of arthritis, especially rheumatoid arthritis and lupus. Plaquenil is usually used for long term disease control, rather than in the short term to control active bursts of inflammation. May 12, 2016 Plaquenil Eye Exams Plaquenil, also known as hydroxychloroquine, is a medication used in the treatment or prevention of malaria. It has also been used to treat other conditions, such as liver disease, that may have been caused by the same parasites that cause malaria.

    Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight.

    Plaquenil ophthalmology

    How Do Ophthalmologists Look for Plaquenil Damage? - American Academy., Plaquenil & Your Eyes

  2. Hyperpigmentation of the skin due to hydroxychloroquine
  3. On examination, a telltale sign of hydroxychloroquine toxicity is a bilateral change in the retinal pigment epithelium of the macula that gives the commonly described appearance of a bull’s-eye. This is a late finding, however, and too late for screening to be useful.

    • Hydroxychloroquine-Induced Retinal Toxicity - American..
    • Plaquenil Eye Exams - Catalina Eye Care.
    • Plaquenil Risk Calculators.

    Apr 20, 2011 Although the incidence of macular toxicity is infrequent with Plaquenil use at a dosage of 200mg or 400mg q.d. its visual impact can be devastating. 2,3. The associated classic retinal toxicity is described as a bull’s eye maculopathy ring of depigmented retinal pigment epithelium that spares the foveal area. Of course the aim is avoid drug related retinal toxicity, which on ophthalmic examination, appears as the classic Bull’s eye change affecting the macula. Once retinal toxicity from hydroxychloroquine occurs, it is thought that the retinal changes are permanent and the disease can progress even if hydroxychloroquine is stopped for 1 to 3 years. We just need to get better at monitoring the eyes and dosing Plaquenil correctly.” New dosing guidelines for Plaquenil, which Lyons worked on, were published in the journal Ophthalmology. Thomas is enthusiastic about the updated guidelines, although he worries that the new dosing recommendations have not been widely disseminated to.

     
  4. nini999 New Member

    Plaquenil (hydroxychloroquine sulfate, Sanofi-Aventis) and the less-used chloroquine are antimalarial drugs with anti-inflammatory properties that are used for the management of a spectrum of inflammatory conditions. Hydroxychloroquine toxicity - EyeWiki Study Raises Questions about Sjogren's and Plaquenil Hydroxychloroquine Oral Route Before Using - Mayo Clinic
     
  5. Submitter New Member

    A 45-year-old black female presented with no ocular or visual complaints. However, her medical history was significant for a recent diagnosis of lupus. What is the blood work protocol while taking. Fasting Blood Test Requirements Important Blood Tests What They Show, Why They’re Done.
     
  6. Nimnul New Member

    Hydroxychloroquine Induced Cardiotoxicity A Rare. Dilated cardiomyopathy was diagnosed. There were no signs or symptoms of an active CTD; her most recent dsDNA, complements, ESR and CRP were normal. A CT coronary angiogram showed normal coronary arteries and a dilated SVC suggestive of pulmonary hypertension. Cardiac MRI revealed global late gadolinium enhancement sparing the subendocardial layer.

    Hydroxychloroquine-Induced Cardiomyopathy Case Report, Pathophysiology.