Derm Net NZ Medical Editor: Dr Delwyn Dyall-Smith, Dermatologist, Wagga Wagga, NSW, Australia. However, following an identical dose of hydroxychloroquine and chloroquine, tissue levels of chloroquine are 2.5 times those of hydroxychloroquine. Derm Net NZ Editor in Chief: Adjunct Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand. Hydroxychloroquine is preferred due to its safer profile. Plaquenil and the sun Chloroquine vs hydroxychloroquine Hydroxychloroquine was well-tolerated, and there was a trend not reaching significance toward reduced medication use and urticarial activity. Combined with a sulfone — A treatment strategy used successfully by the author to circumvent the long latency time of hydroxychloroquine is to start either dapsone or sulfasalazine at the same time. Urticarial vasculitis is a clinico-pathologic entity typified by recurrent episodes of urticaria that have the histopathologic features of leukocytoclastic vasculitis. The cutaneous features may include painful, burning or pruritic skin lesions, the persistence of individual lesions greater than 24 hours, palpable purpura, pronounced central clearing of lesions, and residual hyperpigmentation. Hypocomplementemic urticarial vasculitis syndrome HUVS is a type III hypersensitivity reaction characterized by urticaria with persistent acquired hypocomplementemia. Although HUVS is uncommon, it is important for physicians to be familiar with this disease, as the initial presentation is often life-threatening angioedema. Hydroxychloroquine is considered safer than chloroquine during pregnancy and lactation. If there is a of hydroxychloroquine, although studies have not usually confirmed this clinical impression. Hydroxychloroquine urticarial vasculitis Hydroxychloroquine Efficacy in Chronic Urticaria - Full., Urticarial vasculitis SpringerLink Plaquenil safe in pregnancy Apr 03, 2017 Vasculitis 5 Drugs to Control This Mysterious Blood Vessel Illness. Once considered a fatal disease, vasculitis is now effectively treated as a chronic condition. Five main drug therapies are. Vasculitis 5 Drugs to Control This Mysterious Blood Vessel.. Angioedema in a 47-Year-Old Woman With Hypocomplementemic.. AB0531 The Role of Hydroxychloroquine in ANCA Positive and.. Hypocomplementemic urticarial vasculitis HUV is a rare form of vasculitis characterized by inflammation of the small blood vessels and low levels of complement proteins in the blood. Some cases of HUV respond to therapies commonly used for the treatment of lupus, including low-dose prednisone, hydroxychloroquine, and. Urticarial vasculitis tends to become a chronic condition and patients should be educated about its course. For most patients, this is a disease that affects the skin, with a minority of patients developing systemic complications. Urticarial vasculitis carries a good prognosis, with most occurrences resolving in months to years. For most people, urticarial vasculitis is a disease of the skin, with a minority of patients developing systemic organ involvement. When it is related to an existing autoimmune disease such as lupus, or cancer, the prognosis may depend on the underlying disease. Because urticarial vasculitis may become chronic, follow-up medical care is essential.