Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Can plaquenil help osteoarthritis Plaquenil wrong medication Does plaquenil help with lupus fatigue Chemical process of chloroquine To the contrary, Kawakami and colleagues observed that the utilization of TNF-a inhibitors is associated with an increased risk of surgical site sepsis as well as deep vein thrombophlebitis in patients undergoing major orthopedic surgery.9 Authors noted a 12.5 percent infection rate in patients with RA on TNF-a therapy in comparison to a 2. Adults with RA or psoriatic arthritis undergoing orthopaedic surgery and taking leflunomide were studied in 2002-2003. The authors found that those on leflunomide at time of surgery had a statistically significant increased risk of infection during wound healing P=0.01 26. Plaquenil is an agent that is designed to prevent malaria and also has some immuno-supressant properties for Rheumatoid arthritis. It could theoretically cause reduction of fusion. If this medication is needed then if an ACDF is required, I would use autograft and if a lumbar fusion is required, I would use BMP. Dr. Corenman Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Plaquenil may also be used for purposes not listed in this medication guide. Plaquenil and orthopedic surgery Lupus and Joint Replacement Surgery What You Should Know, The Safety of Elective Surgery with Concurrent Use of Immunosuppressants Plaquenil facial swellingMagnesium with hydroxychloroquinPlaquenil toxicity macula octChloroquine couponChloroquine diphosphate salt chem-impex Grennan DM, Gray J, Loudon J, Fear S 2001 Methotrexate and early postoperative complications in patients with rheumatoid arthritis undergoing elective orthopaedic surgery. Ann Rheum Dis 4–217 PMC free article Perioperative Management of Medications Used in the Treatment of.. Plaquenil - neck and back. Despite Plaquenil dosing recommendations, retinal toxicity.. Plaquenil hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Jun 09, 2006 Despite improved medical therapy, many RA patients still require orthopedic surgery, most frequently total joint arthroplasty. These surgical techniques have also improved, with infectious complications seen in primary arthroplasty dropping from over 10% to 20% in the earliest series to the current rates of 1% 1.