Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. Plaquenil sideceffects Plaquenil and low dose naltrexone Gene rdh12 chloroquine retinopathy Plaquenil 300 mg With all of the physical and emotional complications that lupus can cause, it’s easy to overlook symptoms that seem minor at first. But take this advice Don’t ignore changes in vision. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. They pretty much all restarted the drug and said they would stay on it cause it was working. I would assume from this that people had sudden and quite severe flares when stopping the plaquenil. There is always the chance that some people might interpret this as withdrawal, but I think it is probably always in the eye of the beholder. Did you take yourself off Plaquenil, or did your doctor tell you to go off it? Plus I will be honest the whole eye site thing even though rare has always freaked me out. I went off of it to see if I can manage not being on it as my lupus isnt as severe as other cases but already I am feeling very fatigued and my legs feel heavy if that makes sense. I can discuss alternatives with my DR at my next appt but my DR feels as though the plaq is the best bet for my level of illness. If so are you just dealing with Lupus symptoms or did you take another med? I'm on Plaquenil, and after the first week's GI upset, I have had no problems with it. Discontinuing plaquenil Hydroxychloroquine Side Effects, Dosage, Uses, and More, Plaquenil Side Effects on Your Eyes and Vision Retinal plaquenil toxicityDefine plaquenil Here are 10 things to keep in mind when using Plaquenil Take it on a regular schedule, meaning at the same time each day. Take Plaquenil EXACTLY as prescribed by your physician. Do not stop taking the medication without first speaking to your doctor. Taking Hydroxychloroquine with food and/or milk can help prevent stomach upset. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Let me tell you what weaning down from Plaquenil is like.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Aug 30, 2011 Continued deterioration in visual function can occur after discontinuing hydroxychloroquine, possibly due to slow clearance from the retina and systemically 9, 12. Screening is important in detecting early retinal toxicity before notable funduscopic changes in order to limit the amount of visual loss. Dr. Fung’s case involved a 48-year-old woman with lupus. Nine years after discontinuing medical therapy, the patient had new scotomas, difficulty reading and progression of bull’s-eye maculopathy. Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said.