Severe malaria should be treated with intravenous (IV) antimalarial medications. As a result, CDC is providing IV artesunate for the treatment of all severe malaria cases. With the discontinuation of IV quinidine, IV artesunate is now the first-line drug for treatment of severe malaria in the United States. Hydroxychloroquine malaria prophylaxis dose Plaquenil and alcohol consumption Chloroquine side effects anxiety Doxycycline plaquenil Chloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, chloroquine is not used to treat severe or complicated malaria and to prevent malaria in areas or regions where chloroquine is known not to work resistance. Infusions should be discontinued as soon as the patient is able to take chloroquine by mouth. Where facilities for intravenous infusion are not available chloroquine can be administered by intramuscular or subcutaneous injection at a dosage of 2.5 mg/kg every 4 hours or 3.5 mg/kg every 6 hours until a total of 25 mg/kg has been given. Prophylaxis Chloroquine injection is used in acute attacks of malaria when the patient is unable to swallow. Dosage & administration Adult 200 to 300 mg chloroquine base by intramuscular or intravenous injection. It should not be given intravenously to children. Contraindications It is unknown when IV artesunate will receive FDA approval, as this process requires an interested drug company to submit a new drug application to FDA. IV artesunate is the recommended World Health Organization (WHO) first-line treatment for severe malaria but is neither FDA-approved nor commercially available in the United States. Chloroquine injection intravenous Chloroquine Indications, Side Effects, Warnings -, WHO Model Prescribing Information Drugs Used in Parasitic. Plaquenil drugs.comDoes hydroxychloroquine tabs disrupt immune systemChloroquine effectivenessClinical pearls hydroxychloroquine It is used in the treatment and prophylaxis of malaria due to susceptible strain of Plasmodium falciparum, P. ovale, P. vivax and P. malariae. ADMINISTRATION. Chloroquine Phosphate Injection is administered by slow intravenous route. The intramuscular route is used where intravenous administration is not possible. Nelbquine Chloroquine Phosphate Injection - Boditreat. General Preparation - Chloroquine Phosphate Injection, Cyanocobalamin.. Cardiovascular toxicity and distribution kinetics of.. Chloroquine injection is used in acute attacks of malaria when the patient is unable to swallow. CONTRA-INDICATIONS Care is needed in administering chloroquine to patients with impaired liver or renal function or with porphyria. WARNINGS DOSAGE AND DIRECTIONS FOR USE Adult 200 to 300 mg chloroquine base by intramuscular or intravenous injection. While timely delivery of IV artesunate is anticipated, healthcare providers should consider treating the patient with an oral treatment while waiting for IV artesunate to arrive. Artemether/lumefantrine Coartem ® is the preferred antimalarial for interim treatment because of its fast onset of action. With the discontinuation of IV quinidine, IV artesunate is now the first-line drug for treatment of severe malaria in the United States. IV artesunate is the recommended World Health Organization WHO first-line treatment for severe malaria but is neither FDA-approved nor commercially available in the United States.