Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. Alternatives to hydroxychloroquine for arthritis Aralen buy Hydroxychloroquine retinopathy side effects Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. Plaquenil damps down the reactiveness of the receptors that send out your “fighters”, which in us is overactive. Rather than strangling the life out of your immune system like steroid meds do, it attenuates the function to closer to normal. Over time it can slightly lower your white cell count. Did you take yourself off Plaquenil, or did your doctor tell you to go off it? Plus I will be honest the whole eye site thing even though rare has always freaked me out. I went off of it to see if I can manage not being on it as my lupus isnt as severe as other cases but already I am feeling very fatigued and my legs feel heavy if that makes sense. I can discuss alternatives with my DR at my next appt but my DR feels as though the plaq is the best bet for my level of illness. If so are you just dealing with Lupus symptoms or did you take another med? I'm on Plaquenil, and after the first week's GI upset, I have had no problems with it. How to taper off plaquenil Let me tell you what weaning down from Plaquenil is like., Stopping plaquenil. DailyStrength Plaquenil worksHydroxychloroquine in diabetesRetinal hypopigmentation discrete plaquenilWeaning off plaquenil Proper Use. Drug information provided by IBM Micromedex Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Hydroxychloroquine Oral Route Proper Use - Mayo Clinic. Stopping Plaquenil - General Discussion - Life With Lupus. Hydroxychloroquine MedlinePlus Drug Information. Hi everybody! I recently went to the doc and he recommended that I try cutting my Plaquenil in half from 400mg to 200mg/day. I have been on it since March, 2002. It's been about a week and I have noticed a few slight changes, mainly a little stiffness in my fingers and feeling a little fatigued. I don't know Plaquenil is used in the treatment of sarcoidosis but its main use is in the treatment of malaria. One of the side effects of taking the drug is that it affects eye sight, and eye tests, especially field of vision tests need to be done every six months. For the four years that I took the drug. Jul 16, 2011 Has anyone's doctor suggested taking plaquenil to help taper off Rheum thinks that plaquenil will help me get to a lower dose of prednisone since I can't get past 7.5 mg without a flare.