It is multifocal and small areas may merge to form larger irregular areas. Symptoms are often absent, but they may include: folliculitis. Malaria chloroquine resistant areas Plaquenil helps fatigue Lichen planus is a common disease that causes inflammation swelling and irritation on your skin or inside your mouth. On your skin, lichen planus causes a rash that is usually itchy. Inside your mouth, it may cause burning or soreness. The cause of lichen planus is usually not known, although possible causes include Lichen planopilaris Courtesy of Bryan Anderson, MD This entity is considered a part of the lichen planus complex, even though typical lesions of lichen planus are not seen in the scalp, and only about 30% of patients may present with typical cutaneous or mucosal lesions of lichen planus elsewhere. When lichen planus develops in the mouth, it often does not cause pain or other symptoms. If this is the case, treatment may not be necessary. When lichen planus causes pain, burning, redness, blisters, sores, or ulcers, it can be treated. Some medicine is applied to the sores. Other medicine comes in pill form. Biopsy from an already scarred area of hair loss is unhelpful. However, it is not always possible to make a diagnosis on biopsy. Lichen planus and plaquenil Lichen planus - Diagnosis and treatment - Mayo Clinic, Lichen Planopilaris - Dermatology Advisor Hydroxychloroquine discoid lupusLupus and plaquenil side effectsIs plaquenil addictivePlaquenil immunosuppressive therapyPharmacokinetics of chloroquine in rats Lichen planus LIE-kun PLAY-nus is a condition that can cause swelling and irritation in the skin, hair, nails and mucous membranes. On the skin, lichen planus usually appears as purplish, itchy, flat bumps that develop over several weeks. In the mouth, vagina and other areas covered by a mucous membrane, lichen planus forms lacy white patches. Lichen planus - Symptoms and causes - Mayo Clinic. Lichen planus Diagnosis and treatment. Plaquenil Lichen Planus - Sclero Forums MAIN - Sclero Forums. On the scalp, lichen planus called lichen planopilaris may cause redness, irritation, and, in some cases, permanent hair loss. On the penis, lichen planus appears similar to lesions on other areas of the skin. In the vulva or vagina, lichen planus may appear as bright red patches or sores. Background Oral lichen planus is chronic and can be debilitating. Topical corticosteroids are most frequently used for treatment, but they are not always effective. Objective Hydroxychloroquine sulfate Plaquenil, an antimalarial agent, was evaluated in an open trial 10 patients for its ability to improve oral lichen planus. Lichen Planopilaris Treatment Of all the alopecias, both non-scarring and scarring, lichen planopilaris is the most difficult to treat. There have been no well-controlled trials documenting the benefit of any therapy in LPP.