Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Whats the dosage that causes plaquenil toxicity Can plaquenil help osteoarthritis Hydroxychloroquine spc Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Tell your doctor immediately if any of these rare but very serious side effects occur severe stomach/abdominal pain, severe nausea/vomiting, easy bleeding/bruising, signs of infection e.g. fever, persistent sore throat, seizures, shortness of breath, swelling ankles/feet, extreme tiredness, dark urine, yellowing eyes/skin. Find information about common, infrequent and rare side effects of Plaquenil Oral. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil seizure Plaquenil hydroxychloroquine sulfate Drug / Medicine Information, Hydroxychloroquine 200 mg Tablets Generic Plaquenil Plaquenil also calledPlaquenil alopeciaPlaquenil sunAllergic reaction to plaquenil She was intubated and sedated, and in the early evening, she was transferred to our institution for further evaluation and treatment. The rheumatology team was consulted immediately upon her arrival to help determine whether her seizures represented a manifestation of neuropsychiatric systemic lupus erythematosus NPSLE. Seizures in Lupus - The Rheumatologist. Common and Rare Side Effects for Plaquenil Oral. ICD-10-CM Diagnosis Code Z79.899 Other long term.. Aminoquinolines may cause epileptic seizures in susceptible individuals. Patients with epilepsy or an otherwise low seizure threshold may be at greater risk. Therapy with 4-aminoquinolines, particularly chloroquine, should be administered cautiously in patients with epilepsy. What is Plaquenil Hydroxychloroquine? Plaquenil is most known for its original purpose treating and preventing malaria. Malaria is a disease caused by parasites that can enter the body through a mosquito bite. The essential ingredient, known as quinine, is derived from the bark of the cinchona plant. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more.