It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Combination methotrexate and plaquenil Chloroquine lysosome sigma What is plaquenil When my hydroxychloroquine isn't working You can take medication to relieve the itching, and the rash should go away after a few weeks to months. And unlike psoriasis, this skin rash rarely comes back. Eczema When Irritants Make Skin. Sep 01, 2017 Maybe you have an allergy due to counter acting should Google that to find out for sure as I know there is a list of things you can't take when using plaquinil. I am not sure if it has sulphur/sulfa in it. I am terribly allergi to sulfa,had a rash just like that and spent 3 days in a bathtub of cold water just to get relief as alegy med did not even touch it. Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil rash wont go away Diaper Rash Won't Go Away What to Do, Plaquenil side effects - @amymae1976 - Scleroderma - 20170901. Plaquenil sjogren's fatigueSulfasalazine taken with hydroxychloroquine Author Topic Sun rash that won't go away Read 1808 times Deb 27. Yes, I get this all the time when I go in the sun. I try my best now to stay out of it. I too have been on Plaquenil for years 11 years but it has only caused this sun sensitivity the past four years. But also anyone with autoimmune issues should not be in the sun anyway. Sun rash that won't go away - Sjogren's World. Plaquenil Side Effects Common, Severe, Long Term -. Your Rash Won't Go Away? Here's 5 Hidden Reasons Why. I started with plaquenil last year, yes it took almost 6 months to get a level in your body, it does help, trust me. I was on Prednisone 7.5 to 10 mg per day, had a bad flair up and I am on 40 mg per day, last Friday the dr.''s told me to go down by 5 mg per week, so from 40mg to 35 mg per day. Since the drug is cumulative in its effects you may be having an allergic reaction. My Father had the same reaction took him 3 weeks to develop it and he had to stop. It took 2 weeks for the rash to go away, but it was the Plaquenil. Now he's on Methotrexate and doing well. I had been taking plaquenil since April for my lupus and sjogrens. It was working really well and just recently my rheumy told that I was in remission. I felt great. Then I had an allergic reaction to the plaquenil - a rash all over my body, neck, arms and legs. I stopped taking it 1 week ago.