I've been on plaquenil for 6 months for suspected Sjogren's syndrome (I don't have antibodies for Sjorgren's or Lupus but I do have Hashimoto's and have all the symptoms for Sjorgren's so the rheumatologist suggested a trial of plaquenil). Basically I've been on the drug since January and saw the rheumatologist on Wednesday to see how things are going. Plaquenil for crohn's Cdc malaria map chloroquine resistance How long for chloroquine to work Plaquenil and pregnancy side effects Aug 27, 2010 i was just curious if i was to try plaquenil again for a few days/weeks if you decide to stop do you have to wean off like a lot of drugs or can you simply stop taking it.thanks. If your rheumatoid arthritis symptoms do not improve, or if they worsen, stop taking the drug and call your doctor. Once you and your doctor are sure the drug works for you, do not stop taking hydroxychloroquine without talking to your doctor. Symptoms of rheumatoid arthritis will return if you stop taking hydroxychloroquine. Yes, if the plaquenil controls your Lupus flares, it is best to not use the prednisone. I hope you can get off of it completely, or at least take a small maintenance dose. Take it very slow, tapering off, and if you have a reaction, severe fatigue, etc, talk to your doc, about tapering down even slower. I do think it's helped with fatigue and muscle pain but it's hard for me to compare to Xmas as when the improvement is so gradual I think it's really hard to notice on a gradual basis. I *think* I'm improving but it's been a gradual process and I said to him that it's quite hard to tell how much of an improvement I'm feeling. Do you have to be weaned off of plaquenil Plaquenil Withdrawal – Life As An Anomaly, Hydroxychloroquine MedlinePlus Drug Information John hopkins research on plaquenil Hi everybody! I recently went to the doc and he recommended that I try cutting my Plaquenil in half from 400mg to 200mg/day. I have been on it since March, 2002. It's been about a week and I have noticed a few slight changes, mainly a little stiffness in my fingers and feeling a little fatigued. Healthboards - Immune & Autoimmune - Lupus tapering Plaquenil. Prednisone and Plaquenil question" Lupus Community - Support Group. Taking Plaquenil for Rheumatoid Arthritis. The lesson here is - for those who need to go off plaquenil, be careful about just going off it cold turkey. Obviously some of CAN do that, but if you don't know if you're one of them - better to be on the safe side and wean slowly. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from 16 million FDA reports. The results are personalized to your gender and age 0-99+. People feel different symptoms of low blood sugar. It is important that you learn which symptoms you usually have so you can treat it quickly. Talk to your doctor about the best way to treat low blood sugar. Hydroxychloroquine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. If.