It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Chloroquine resistant malaria treatment in children Plaquenil 200 mg indications Plaquenil and prednisone What are the side effects of hydroxychloroquine and sulfasalazine in treating rheumatoid arthritis? ANSWER Hydroxychloroquine Plaquenil and sulfasalazine Azulfidine are used for mild. User Reviews for Hydroxychloroquine to treat Rheumatoid Arthritis. Also known as Plaquenil, Quineprox. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Overview; Side Effects; Dosage Susceptibility to rheumatoid arthritis RA is associated with defined HLA-DRB1 alleles. However the molecular basis of this association is not known. Peculiarities in the expression of disease-linked DRB1 alleles could be involved since in healthy controls HLA-DRB1 gene expression varies according to the alleles in B cells. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hla-dr4 rheumatoid arthritis and hydroxychloroquine Rheumatoid Arthritis 17 Signs of Serious Complications, Hydroxychloroquine User Reviews for Rheumatoid Arthritis at. Stopping plaquenil for raPlaquenil usoGastritis plaquenil Definition The major histocompatibility complex locus designated HLA-DR4 was first associated with RA in studies reported by Stastny in 1978. Using the technique of mixed lymphocyte culture, patients with RA were found to be more alike than were normal individuals, suggesting the presence of a shared cell-associated antigen. RheumaKnowledgy HLA-DR4. HLA-DRB1 gene transcripts in rheumatoid arthritis. Hydroxychloroquine - Side Effects, Dosage, Interactions.. I am a 17 year old female with Juvenile Idiopathic Rheumatoid Arthritis. I take enbrel, methotrexate, and prednisone. I just spoke with my doctor at Vanderbilt Children’s Hospital, and he told me to continue taking all of my medications except prednisone and any other anti-inflammatory medication Advil, Tylenol, etc. HLA-DR4 DR4 is an HLA-DR serotype that recognizes the DRB1*04 gene products. The DR4 serogroup is large and has a number of moderate frequency alleles spread over large regions of the world. The DR4 serogroup is large and has a number of moderate frequency alleles spread over large regions of the world. Plaquenil is a DMARD which has been prescribed for years to treat rheumatoid arthritis, lupus, juvenile rheumatoid arthritis, and other autoimmune diseases. When the first biologic DMARD received FDA-approval in 1998, and as other biologics followed in subsequent years, it appeared as though Plaquenil would become less prescribed.