My peripheral neuropathy actually went away too, and my rheumy thinks it was a rare, toxic side-effect of the Plaquenil. Get emergency medical help if you have any of these signs of an allergic reaction while taking hydroxychloroquine: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Fatigue is part of malaria, which is the normal use of this medication. Pharmacokinetics of chloroquine Ra treatment hydroxychloroquine Answering this question should help allergists treat chronic urticaria with a more evidence based approach. To date there has one been one prospective trial evaluating hydroxychloroquine in hives, and although it showed a trend towards efficacy 0.05p0.10, it was not statistically significant. Hi There, Ok, I just started taking Plaquenil 7 days ago and I just realized I am really really itchy. I looked down at my arms and I have red and white blotchy areas on my forarms. I am starting to itch in my scalp, back, stomach, face and arms now. I think this rash is just starting, so I don't know if it will Plaquenil itself probably does not have a direct affect on your immune system - it is a DMARD and is not considered to be an immunosuppressant. However, many with active autoimmune diseases feel that they are not succeptible to many of the common viruses that they are exposed to - somewhat of a silver lining. This is not a complete list of side effects and others may occur. Call your doctor at once if you have a serious side effect such as:muscle weakness, twitching, or uncontrolled movement;loss of balance or coordination;blurred vision, light sensitivity, seeing halos around lights;pale skin, easy bruising or bleeding;confusion, unusual thoughts or behavior; orseizure (convulsions). Less serious side effects of hydroxychloroquine may include:headache, ringing in your ears, spinning sensation;nausea, vomiting, stomach pain;loss of appetite, weight loss;mood changes, feeling nervous or irritable;skin rash or itching; or hair loss. Will plaquenil help autoimmune urticaria Impact of hydroxychloroquine therapy on chronic urticaria., Immune & Autoimmune - Lupus Anyone Get An Itchy Rash From Does hydroxychloroquine help osteoarthritisCan you take phenylephrine with plaquenil Plaquenil is a DMARD which has been prescribed for years to treat rheumatoid arthritis, lupus, juvenile rheumatoid arthritis, and other autoimmune diseases. When the first biologic DMARD received FDA-approval in 1998, and as other biologics followed in subsequent years, it appeared as though Plaquenil would become less prescribed. Taking Plaquenil for Rheumatoid Arthritis. Anyone on Hydroxychloroquine plaquenil - Autoimmune.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. My new allergist said that he may have a treatment for me! Plaquenil. It was originally made for Lupus, which is also an auto immune disease, but apparently it helps in the treatment of hives. I am so excited to start taking and finally be able to get some relief from all of this! Has anyone else taken Plaquenil? A 1-year follow-up study has shown efficacy of CsA in treatment of autoimmune urticaria, even in low doses 1.5-2.5 mg/kg/day given over 5 months. The main side effects occurring with CsA are renal damage which may be reversible on stopping medications and hypertension. Plaquenil hydroxychloroquine is a medication most known for its original purpose of treating or preventing malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Today, Plaquenil and other antimalarials are also used to treat and help prevent symptoms caused by certain autoimmune diseases such as.