Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. I need an eye exam for plaquenil Sulfasalazine and hydroxychloroquine rheumatoid arthritis Optometric testing for plaquenil toxicity Plaquenil toxicity isn’t even in the top 10, or the top 100” if you’re looking at incidence, he said. “It’s a pretty rare thing.” Nevertheless, he urged doctors to master the Academy’s new guidelines, because the effects from chloroquine and hydroxychloroquine, when they do occur, are severe and often irreversible. Two months, but it may take up to six months before full benefits of this medication are experienced. Although there are few drug interactions with hydroxychloroquine, to be safe be sure to tell your doctor about all of the medications you are taking, including over-the-counter drugs and natural remedies. Be sure to notify your other physicians. Do I need a prescription for hydroxychloroquine Plaquenil? What are the side effects of hydroxychloroquine Plaquenil? What is the dosage for hydroxychloroquine Plaquenil? Which drugs or supplements interact with hydroxychloroquine Plaquenil? Is hydroxychloroquine Plaquenil safe to take if I'm pregnant or breastfeeding? Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). How often do you take plaquenil DMARDs for Treating Rheumatoid Arthritis, PATIENT FACT SHEET Hydroxychloroquine Plaquenil Chloroquine resistant malaria drugHow to tell if plaquenil is workingPlaquenil and bc Research has shown that your risk of developing retinopathy is higher the longer you are taking Plaquenil. In fact, the incidence of retinal toxicity rises sharply in people that have taken it between 5 and 7 years. As a result, baseline testing should occur within the first year of taking the drug and then annually at the five-year mark. Plaquenil Side Effects on Your Eyes and Vision. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. New Plaquenil Guidelines. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few months, but it can take up to six months for full effects. Her medical history was significant for Plaquenil therapy spanning 12 years with a daily dose of 200mg twice daily. She presented with a best-corrected visual acuity of 20/20 OD and 20/20 OS. All preliminary testing revealed normal findings. New Plaquenil dosing guidelines increase safety. 135 lbs. or more, any height - up to 400 mg Plaquenil daily. 102 lbs. to 134 lbs. - up to 300 mg Plaquenil daily. 101 lbs or less - up to 200 mg Plaquenil daily.