Natural killer cells are part of the body's natural immune system and typically respond to viruses and tumors. Studies suggest that some women who experience recurrent miscarriages, may have higher levels of natural killer cells. Patch trial hydroxychloroquine Plaquenil and flagyl together What is plaquenil good for Summary. Chloroquine is an anti-malarial drug available at pharmacies for people traveling to area with malaria risks. Note based on a RGCC chemosensitivity analysis I have seen at a German clinic, Hydroxychloroquine has been effective in killing the cancer cells of 5 out 7 patients that were tested. The exact hydroxychloroquine mechanism of action is unclear, although it does work to interrupt the communication of immune system cells to decrease swelling, pain, and joint damage. 1, 2, 3, 5 From the community “My Rheumatologist recently put me on Hydroxychoroquine for treating osteoarthritis and joint cysts in my hands and every other. Hydroxychloroquine may prevent autophagy, a normal process in which a cell destroys proteins and other substances which may lead to cell death. Autophagy may prevent normal cells from developing into tumor cells, but it may also protect tumor cells by destroying anticancer drugs or substances taken up by them. Natural killer cells actually help with the process of an embryo implanting in the uterus. Doctors theorize that the natural killer cells may treat a pregnancy like a foreign invader and attack it. Hydroxychloroquine natural killer cells Hydroxychloroquine Uses, Dosage & Side Effects -, Hydroxychloroquine Plaquenil Success, Reviews and Side Effects Plaquenil pharmacologyChloroquine retinal cellHydroxychloroquine dose based on weight and renal function Hydroxychloroquine increases lysosomal pH in antigen-presenting cells. In inflammatory conditions, it blocks toll-like receptors on plasmacytoid dendritic cells PDCs. citation needed Hydroxychloroquine, by decreasing TLR signaling, reduces the activation of dendritic cells and the inflammatory process. Hydroxychloroquine - Wikipedia. Clinical Trials Using Hydroxychloroquine - National Cancer.. Hydroxychloroquine DermNet NZ. The main goal of this research study is to determine whether treating patients with renal cell cancer with the study drug hydroxychloroquine along with the IL-2 aldesleukin can make the cancer easier to kill and eliminate. Another goal is to see how the study drug affects the body’s immune cells which fight cancer cells. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells. Rare but potentially serious eye toxicity can occur. This toxicity affects a part of the eye called the retina and can lead to color blindness and even loss of vision. An. As a lysosomotropic agent, hydroxychloroquine raises intralysosomal pH, impairing autophagic protein degradation; hydroxychloroquine-mediated accumulation of ineffective autophagosomes may result in cell death in tumor cells reliant on autophagy for survival.