The clinical trials on this list are studying Hydroxychloroquine. NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. Is hydroxychloroquine a hydrocodone Screening criteria for ocular toxicity of plaquenil Plaquenil and suicidal thoughts Hydroxychloroquine and Gefitinib to Treat Lung Cancer The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U. S. Federal Government. One of the treatments for small cell lung cancer SCLC is chemotherapy. The chemotherapy most often used is a carboplatin and etoposide. This is a standard treatment. Recent research shows that a drug called hydroxychloroquine HCQ might help chemotherapy work better. Rheumatoid Arthritis Drug Linked to Cancer. Nov. 16, 2004 -- For people with rheumatoid arthritis, methotrexate is the treatment of choice in reducing pain and inflammation. But there's evidence the drug can activate a virus that can increase the risk of lymphoma and similar cancers in some patients. Talk to your doctor for help in deciding if one is right for you. You may want to think about taking part in a clinical trial. Hydroxychloroquine and lung cancer RA Drugs and Cancer What’s the Link?, A trial of chemotherapy and hydroxychloroquine for small. Methotrexate and plaquenil for rheumatoid arthritisPregnancy category hydroxychloroquineAf plaquenil Cancer plus an additional drug, hydroxychloroquine. The standard treatment for lung cancer. being used includes 2 chemotherapy drugs, called paclitaxel and carboplatin, plus a drug. that targets blood vessels, called bevacizumab also known as avastin. Hydroxychloroquine + Carboplatin, Paclitaxel and Bevacizumab in Non.. Rheumatoid Arthritis Drug Linked to Cancer - WebMD. Will you have Interstitial lung disease with Plaquenil.. Researchers reveal how two drugs used to treat malaria, called chloroquine and hydroxychloroquine, could help in the fight against cancer. Studies in genetically engineered mouse models demonstrate that autophagy inhibition suppresses lung tumor development and progression, especially in Kras mutated tumors. We report safety and efficacy of adding an autophagy inhibitor, hydroxychloroquine HCQ to front-line platinum-based chemotherapy in a phase Ib single arm study in patients with metastatic NSCLC. Hydroxychloroquine HCQ, one of the classic anti-malarial drugs, has been used to treat cancer in several preclinical studies and clinical trials. Previous study suggested that HCQ was active in suppressing cell migration and metastasis, both in vitro and in vivo 4.