Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Quarantine procedure for saltwater fish chloroquine What should a nurse monitor when taking hydroxychloroquine Hydroxychloroquine yellow Moved Permanently. The document has moved here. Overdose. Hydroxychloroquine is very toxic in overdosage; overdosage is extremely hazardous and difficult to treat. Urgent advice from the National Poisons Information Service is essential. Life-threatening features include arrhythmias which can have a very rapid onset and convulsions which can be intractable. We report safety and efficacy of adding an autophagy inhibitor, hydroxychloroquine HCQ to front-line platinum-based chemotherapy in a phase Ib single arm study in patients with metastatic NSCLC. Methods Patients with newly diagnosed metastatic NSCLC were treated with carboplatin, paclitaxel and bevacizumab if meeting criteria and HCQ 200 to 600 mg BID for the escalation part and 600 mg BID for the expansion. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Neutropenia hydroxychloroquine Neutropenia in Felty's syndrome successfully, HYDROXYCHLOROQUINE SULFATE Drug BNF content published. Plaquenil ingredients Introduction Hydroxychloroquine is a Aminoquinoline derivative which is widely used for treatment of malaria, rheumatoid arthritis and lupus besides many other autoimmune diseases. Though neutropenia is listed as a potential side effect, there is no reported case in the literature. We present a very rare presentation of hydroxychloroquine toxicity. Hydroxychloroquine induced profound neutropenia with.. Modulation of autophagy with hydroxychloroquine in patients with.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil hydroxychloroquine is a medication most known for its original purpose of treating or preventing malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Neutropenia is a decrease in circulating neutrophils in the nonmarginal pool, which constitutes 4-5% of total body neutrophil stores. Most of the neutrophils are contained in the bone marrow, either as mitotically active one third or postmitotic mature cells two thirds. A case of hydroxychloroquine-induced agranulocytosis in a patient with discoid lupus erythematosus is reported. The patient had previously received chloroquine therapy for several months. Leukopenia preceded the appearance of agranulocytosis, and persisted for six weeks following clinical recovery.