Systemic lupus erythematosus (SLE) is an autoimmune disease that may affect nearly any organ system in the human body. When this disease affects the kidney, it is termed . Hydroxychloroquine and folic acid High cost of hydroxychloroquine Lupus nephritis nef-RYE-tis is the medical name for kidney swelling and irritation that is caused by lupus. Lupus is an autoimmune disease. Autoimmune diseases cause your immune system to attack your own healthy cells. Jun 20, 2012 The treatment of membranous lupus nephritis, ISN/RPS class V, differs from that of proliferative nephritis. Milder disease with stable kidney function, subnephrotic proteinuria, and the absence of proliferative lesions may only require treatment with an ACE inhibitor or an ARB in order to suppress the renin-angiotensin-aldosterone system RAAS. Aralen Chloroquine Aralen is a prescription medication approved by the Food and Drug Administration FDA in 1949 to treat malaria. Aralen is also prescribed to treat inflammation associated with lupus. Aralen is also known by its drug name, Chloroquine. Even with the many recent advances in treatments for lupus nephritis, 10% to 15% of treated patients will still progress to end-stage renal disease (ESRD) and require dialysis or transplant. The condition is often associated with poorer outcomes and is of particular interest for this reason. Chloroquine lupus nephritis Chloroquine in Lupus Prevents flares and saves lives., Current Therapies for Lupus Nephritis - U. S. Pharmacist Chloroquine side effects itching Lupus Nephritis Call for Guideline Development Partners The ACR invites letters of interest from those who wish to partner with ACR to develop new clinical practice guidelines for the prevention and treatment of lupus nephritis. Clinical Practice Guidelines Lupus Nephritis. Aralen Chloroquine MyLupusTeam. Lupus nephritis - Diagnosis and treatment - Mayo Clinic. Hydroxychloroquine HCQ is a recommended drug in systemic lupus erythematosus SLE. It has a long terminal half-life, making it an attractive target for therapeutic drug monitoring. The aim of this study was to establish a relationship between blood HCQ concentration and lupus nephritis activity. While lupus nephritis impacts 40% of lupus patients, it is far more common in nonwhite populations and affects women more than men. According to data from a 2000-2004 Medicaid study, lupus nephritis is 3.8 times more likely in blacks, 3.7 times more in Asians, 2.3 times more in Native Americans, and 1.9 times more in Hispanics. Lupus nephritis is one of the most serious complications of lupus. It occurs when SLE causes your immune system to attack your kidneys — specifically, the parts of your kidney that filter your.