It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Diazepam with plaquenil Chloroquine resistant vivax malaria treatment I may be wrong I often am! but I think there are more listed side effects for aspirin than there are for plaquenil; and by a very long shot, it would seem to be safer than steroids, especially for scleroderma patients. Basically, plaquenil's effect is to modulate the immune system, which is something that could be quite beneficial for some of us. Hydroxychloroquine Plaquenil is a mild DMARD disease-modifying anti-rheumatic drug and it’s use for the treatment of systemic scleroderma and other autoimmune conditions is extremely common. Others target specific aspects of the disease, such as the mechanisms involved in skin fibrosis. An example would be imatinib mesylate Gleevec. A third category involves medications that are used to “regulate” the immune system, such as hydroxychloroquine Plaquenil. Potential Side Effects of Scleroderma Medications Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine scleroderma How effective is Hydroxychloroquine sulfate for Systemic., Hydroxychloroquine - @trampmom - Scleroderma - 20171022. Plaquenil 40 mgChloroquine tablet price Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs. The disease can be either localized to the skin or involve other organs in addition to the skin. Symptoms may include areas of thickened skin, stiffness, feeling tired, and poor blood flow to the fingers or toes with cold exposure. Scleroderma - Wikipedia. Scleroderma Treatment General – Standard - Scleroderma Education Project. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Evaluation of a patient decision aid PtDA for initiating disease modifying anti–rheumatic drugs. The PtDA can be a valuable aid in improving patient participation in decision–making about disease modifying anti–rheumatic drugs DMARDs. BioMed Central, Arthritis Research & Therapy, 10/28/2016. Hydroxychloroquine is considered safer than chloroquine during pregnancy and lactation. Hydroxychloroquine is rapidly absorbed from the gastrointestinal tract, and steady-state concentrations are reached after 4–6 weeks; 45% of hydroxychloroquine binds to plasma proteins that are deposited in tissues such as the liver, spleen, kidney, and lung. Anti-malarial drugs, such as Plaquenil hydroxychloroquine, is often used to manage lupus and can also be effective in scleroderma. Plaquenil is thought to interfere with communication between immune cells, which can suppress the damaging effect of an overly active immune response without raising a patient’s risk of susceptibility to infections.