In TTP, blood clots form in small blood vessels throughout the body. The clots can limit or block the flow of oxygen-rich blood to the body's organs, such as the brain, kidneys, and heart. The increased clotting that occurs in TTP also uses up platelets (PLATE-lets) in the blood. Hydroxychloroquine Is plaquenil an anti inflammatory drug Chloroquine calcium phosphate transfection Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Aug 14, 2017 According to the New Zealand Dermatological Society, Plaquenil can cause abnormalities in blood counts. An abnormally low number of white blood cells can lead to infection, because white blood cells defend the body against bacteria. Low platelet count thrombocytopenia can lead to easy bleeding and bruising. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. These cell fragments stick together to seal small cuts and breaks on blood vessel walls and stop bleeding. Platelets are blood cell fragments that help form blood clots. Thrombocytopenia plaquenil Haematological manifestations of lupus Lupus Science & Medicine, Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Pill image hydroxychloroquine 200mg tabletsHow does chloroquine workPlaquenil drug guideChloroquine side effects on eyePlaquenil for chronic urticaria PLAQUENIL tablets are white, to off-white, film coated tablets imprinted “PLAQUENIL” on one face in black ink. Each tablet contains 200 mg hydroxychloroquine sulfate equivalent to 155 mg base. Bottles of 100 tablets NDC 59212-562-10. Do not crush or divide PLAQUENIL film-coated tablets see DOSAGE AND ADMINISTRATION. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Hydroxychloroquine - Wikipedia. A case of thrombocytopenia associated with the use of.. PLAQUENIL hydroxychloroquine sulfate tablets is indicated for the treatment of rheumatoid arthritis, and discoid and systemic lupus erythematosus, in patients who have not responded satisfactorily to drugs with less potential for serious side effects. If any severe blood disorder such as aplastic anemia, agranulocytosis, leukopenia, or thrombocytopenia, appears which is not attributable to the disease under treatment, consider discontinuation of Plaquenil. Plaquenil should be administered with caution in patients having glucose-6-phosphate dehydrogenase G-6-PD deficiency. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days.