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Sublethal concentrations of various antibiotics markedly impair bacterial adhesion to human cells, by affecting the adherence properties of microorganisms. Intermittent antibiotic doses generally cause oscillations in drug concentrations at an infection site, exceeding MIC values for a limited period only. lasix toxicity If you're reading this article, you may have been prescribed ciprofloxacin (Cipro), levofloxacin (Levaquin) or some other type of fluoroquinolone for the treatment of a bacterial infection (think respiratory or urinary tract infection). Overall, these drugs are safe and effective against a wide array of gram-positive and gram-negative bacterial pathogens making them a good choice for systemic or body-wide treatment. At the core of all fluoroquinolones—including drugs like ciprofloxacin and levofloxacin—are 2 six-member carbon rings attached to a fluoride atom. 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