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The question is almost irrelevant (assuming it’s skin-related) because if you’re asking me or any beauty editor with more than five minutes' experience what to do about pretty much any skin issue — acne, fine lines, brown spots, drooping, dullness, dark circles, enlarged pores — retinol will likely be central to the solution. Along with a bunch of other vitamin-A derivatives starting with the letter R, retinol is an example of a retinoid — that’s the catchall term for these A-based formulas, both the over-the-counter (OTC) and prescription varieties. This directive can translate to countless improvements — normalized cell turnover for clear, glowing skin; balanced pigment production for fewer splotches; revved-up collagen synthesis for smoother skin and tighter pores — but it generally comes with an irksome adjustment period. OTC vitamin-A creams, like retinol and retinaldehyde, tend to be weaker because the skin has to convert them to retinoic acid before using them. 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