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    If you're trying to lose weight, you might consider a diet pill like Xenical or alli. Both weight loss aids contain the same medication, called orlistat, but in different amounts. Xenical is the prescription dose (120 mg) of orlistat. Xenical is approved by the Food and Drug Administration and intended to be used by individuals with a body mass index (BMI) of 30 or more or a BMI of 27 along with a weight-related condition like type 2 diabetes or hypertension. Xenical can also be used for people who have lost weight and want to prevent weight regain. Xenical is designed to be used along with a low-fat, low-calorie diet. Those who lose weight with the medication are more likely to be successful over the long-term and keep the weight off for good if they follow a healthy lifestyle. This type of medication is called a lipase inhibitor because it helps your body to absorb less fat from the food that you eat. Orlistat is a powerful medication meant for people who are overweight or obese. Both Alli and Xenical are specifically approved to be taken only while also adhering to a low-calorie diet and exercise program. The OTC version, Alli, contains half as much as orlistat as doctor-prescribed Xenical does. Orlistat works by blocking enzymes in the gut that normally digest fat, thus preventing its absorption. (During our review of the latest information one of our medical consultants commented that "fat malabsorption," as the condition is known, is actually a disease.) But that lack of absorption can lead to a number of adverse effects. In clinical trials of Xenical, during the first year of use, 27 percent of people experienced oily underwear staining, 24 percent had gas with involuntary discharge of stool, 22 percent experienced fecal urgency, 11 percent had an increased number of bowel movements, and 8 percent suffered fecal incontinence. Virtually everyone who takes orlistat experiences diarrhea, at least, occasionally.

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