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    The release of interleukin (IL)-10, IL-6, interferon-γ and IL-8 was inhibited only at the highest erythromycin concentration. Inhibition of TNF-α production by erythromycin may, at least in part, explain the efficacy of this macrolide during panbronchiolitis despite its lack of activity for Thus erythromycin may have therapeutic value for various infectious and inflammatory disorders independent of its antimicrobial properties. Erythromycin has been reported to be effective in the treatment of chronic inflammatory conditions of the lower respiratory tract, such as diffuse panbronchiolitis. Diffuse panbronchiolitis is characterized by chronic inflammation in the respiratory bronchioles with infiltration of plasma cells and lymphocytes. The chronic inflammatory lesions often extend to the more proximal bronchioles, leading to secondary bronchiectasis in the more advanced stages. Early in the course of the disease sputum cultures are often positive for activity were purchased from: imipenem (Merck Sharp and Dohme, Haarlem, The Netherlands); ceftazidime (Glaxo, Zeist, The Netherlands); gentamicin (Centrafarm, Etten-Leur, The Netherlands); and ciprofloxacin (Bayer, Mijdrecht, The Netherlands). Only clinically relevant concentrations were used in whole blood stimulations (erythromycin, imipenem and ceftazidime 10 (serotype PA103) was obtained from a clinical isolate. Erythromycin is used to prevent or treat individuals with bacterial infections. The Online Clinic can prescribe Erythromycin for a number of infections. Click on the Free Consultation button and choose the most relevant consultation type. Erythromycin is a member of the macrolide group of antibiotic medicines. Erythromycin may be used to treat a variety of bacterial infections of the eye, ear, nose, throat, respiratory tract, gastrointestinal system, skin, and soft tissues. It may also be used to prevent infections in situations of surgery, trauma, and burns, or in cases of rheumatic fever, scarlet fever, diphtheria, osteomyelitis, urethritis, and prostatitis. Erythromycin acts on susceptible strains of bacteria, inhibiting their growth and preventing them from reproducing.

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