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    The originally marketed human drug is called Prozac®. Fluoxetine increases serotonin levels within the central nervous system by preventing the re-uptake of serotonin at the level of the presynaptic neuron. This allows serotonin to accumulate in the synaptic cleft and affect the post-synaptic neuron. Serotonin is the neurotransmitter responsible for facilitating social interactions, general awareness, coping mechanism, and adaptability. SSRI drugs commonly are prescribed for humans as a part of the treatment of depression, anxiety disorders, compulsive disorders, and difficulty managing aggression. Fluoxetine must be administered for four to eight weeks before the full effect on serotonin levels is realized. Although the bioavailability of transdermal fluoxetine is only about 10% of that of the oral medication, it may be an alternative when oral administration is not feasible or safe. Fluoxetine is FDA-approved for use in separation anxiety in dogs. canadian pharmacies online prescriptions Reconcile, fluoxetine, is a prescription serotonin reuptake inhibitor (SSRI) antidepressant medication. It works by affecting serotonin levels in the brain that may be unbalanced in dogs with certain behavior and cognitive disorders. Reconcile is commonly prescribed to treat separation anxiety in dogs, and help relieve behavioral symptoms which may include household destruction, indoor elimination, excessive vocalization, excessive salivation, frequent pacing. Reconcile is a flavored, chewable tablet available in 30 ct bottles and four strengths 8 mg, 16 mg, 32 mg, and 64 mg. Consult with your dog’s veterinarian before administering this medication and follow their specific instructions for use.

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